Expanding Cell Tropism of HIV-1
Expanding Cell Tropism of HIV-1
Anne-Mieke Vandamme
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*Correspondence: Anne-Mieke Vandamme, Email not available
Abstract
Although CD4 is still the main receptor for HIV-1, with CD4-positive cells the main target cells,recent results suggest that the cell tropism ofHIV-1 is larger than previously appreciated. Sahaet al. (Nature Medicine 2001; 7: 20-1) reportedfor the first time the characterisation of a primaryisolate with dual tropism, using independently eitherCD4 or CD8 as receptor.
