Management of Kaposi’s Sarcoma in Resource-limited Settings in the Era of HAART

Management of Kaposi’s Sarcoma in Resource-limited Settings in the Era of HAART

Lut Lynen 1, Maria Zolfo 1, Veerle Huyst 1, Francoise Louis 1, Pieter Barnardt 1, Ann van de Velde 1, Caroline de Schacht 1, Robert Colebunders 1

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*Correspondence: Ann van de Velde, Email not available

Abstract

The introduction of highly active antiretroviral therapy (HAART) has changed the natural history of AIDS-associated Kaposi’s sarcoma (KS). Although the use of HAART remains limited in low-resource settings, there are global initiatives to make these drugs available to several millions of HIV-infected persons. While there are multiple reports of KS regression during HAART with or without chemotherapy, there is little documentation on KS management in resource-limited settings. In this paper we review current KS treatments available worldwide and discuss the implications of the increased access to antiretrovirals for KS treatment strategies in resource-limited settings.

Keywords: Kaposi’s sarcoma. AIDS. HAART. Resource-limited settings. Developing countries.

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