New Trials Comparing Protease Inhibitors and Nonnucleoside Analogs will Assess Reductions in Cardiovascular Risk Besides Antiviral Efficacy in First-line Therapies

New Trials Comparing Protease Inhibitors and Nonnucleoside Analogs will Assess Reductions in Cardiovascular Risk Besides Antiviral Efficacy in First-line Therapies

Francisco Blanco

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*Correspondence: Francisco Blanco, Email not available

Abstract

Boehringer Ingelheim recently announced theinitiation of a new clinical trial, called NewArT, thatwill compare the efficacy and safety of the NNRTInevirapine (Viramune®) versus the ritonavir-boostedprotease inhibitor atazanavir (Reyataz®, Bristol-Myers Squibb). The study will enroll 150 HIV treatment-naive patients from 18 planned sites acrossthe USA. Both agents will be combined with thefixed-dose combination of tenofovir and emtricitabine(Truvada®, Gilead Sciences).

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