Liver and Kidney Transplantation in HIV-Infected Patients

Liver and Kidney Transplantation in HIV-Infected Patients

Clara C. Tan-Tam 1, Lynda A. Frassetto 1, Peter G. Stock 1

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*Correspondence: Clara C. Tan-Tam, Email not available

Abstract

HIV infection has evolved into a chronic condition as a result of improvements in therapeutic options.Chronic exposure with HIV and associated co-pathogens as well as toxicities from prolonged therapywith antiviral medications has resulted in increased morbidity and mortality rates from end-stage liverand kidney disease in the HIV-infected population. Since the definitive treatment for end-stage organfailure is transplantation, demand has increased among HIV-infected patients. Although the transplantcommunity has been slow to recognize HIV as a chronic condition, many transplant centers haveeliminated HIV infection as a contraindication to transplantation as a result of better patient managementand demand. This review examines the current clinical strategies and issues surrounding liver andkidney transplantation in HIV-infected patients.

Keywords: HCV. HBV. Transplant. Renal. Hepatic. End-stage organ failure.

Contents

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