Do Integrase Inhibitors Impact on the HIV Reservoir?
Carolina Garrido 1, Carmen de Mendoza 2
1 NULL; 2 Puerta de Hierro University Hospital, Madrid, Spain
*Correspondence: Carmen de Mendoza, Email not available
Abstract
The introduction of combination antiretroviral treatment has represented a great milestone in the management of HIV-infected individuals, with large benefits in survival and quality of life. The achievement of this landmark has prompted the exploration of further goals, including the eradication of HIV infection once established. Since the biggest problem for eradicating the virus from the organism is the integration of the HIV genome into the host cells, the arrival of integrase inhibitors has renewed the expectations for a cure for AIDS. Several studies have recently explored this hypothesis and their conclusions merit some thoughts.
