New Antiretroviral Treatment Guidelines from the IAS-USA Panel
Pablo Labarga 1, Francisco Blanco 1
1 NULL
*Correspondence: Francisco Blanco, Email not available
Abstract
The International Antiviral Society-USA Panel (formerly International AIDS Society-USA Panel) issued this summer a new edition of the antiretroviral treatment guidelines (Thompson, et al. JAMA. 2012;308:387-402). Certainly, the most outstanding and innovative proposal concludes that in established HIV infection, antiretroviral therapy should be offered to all individuals regardless of CD4 cell counts. This statement is mainly based on extensive data from large cohort studies demonstrating that antiretroviral therapy protects from non-AIDS-related complications and reduces the risk of sexual transmission of HIV. The new guidelines also extend treatment to all individuals in the acute phase of primary HIV infection, regardless of the presence of symptoms. The only subset of HIV individuals for whom antiretroviral therapy may be deferred is represented by elite controllers and long-term nonprogressors.
