HIV Protease Inhibitors Associated with Increased HCV Viral Load in Coinfected Patients
HIV Protease Inhibitors Associated with Increased HCV Viral Load in Coinfected Patients
Pablo Labarga
NULL
*Correspondence: Pablo Labarga, Email not available
Abstract
Increases in serum HCV-RNA of 1 log on average after initiation of antiretroviral therapy have been reported in HIV/HCV-coinfected patients (Chung, et al. AIDS. 2002;16:1915-23). Accordingly, coinfected individuals on antiretroviral therapy depict greater HCV viremia than HCV-monoinfected individuals (Barreiro, et al. J Clin Virol. 2015;71:63-6). This observation could contribute to explaining lower treatment response rates in the coinfected population, even using the new oral direct-acting antivirals.
