Effect of HIV Infection on the Course of Syphilis
Gilles Pialoux 1, Sophie Vimont 1, Antoine Moulignier 1, Marion Buteux 1, Bruno Abraham 1, Philippe Bonnard 1
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*Correspondence: Antoine Moulignier, Email not available
Abstract
Syphilis has been a public health problem for centuries. Syphilis and HIV form a dangerous combination:syphilis significantly increases the risk of contracting HIV infection, and HIV can alter thenatural course of syphilis. Despite a better understanding of the interaction between these twodiseases, many controversies persist. The incidence of syphilis has increased among HIV-infectedpatients both in Europe and in the USA, and especially in the homosexual/bisexual transmissiongroup. We discuss the interaction between HIV/AIDS and syphilis in a review of the most recentliterature, focusing particularly on the diagnosis, treatment, and follow-up of HIV-infected patientswith syphilis. Early diagnosis of syphilis in HIV-infected patients requires awareness among bothpatients and clinicians. Early treatment of syphilis is crucial as it reduces the risk of transmission.
