Caution with New Oral Hepatitis C Drugs

Caution with New Oral Hepatitis C Drugs

Vicente Soriano 1, Isabella Esposito 2

1 UNIR Health Sciences School and Medical Center, Universidad Internacional de La Rioja, Madrid, Spain; 2 NULL

*Correspondence: Isabella Esposito, Email not available

Abstract

The hepatitis C field is living a revolution following the introduction of all-oral therapies that can cure most patients with short courses of direct-acting antiviral (DAA) combinations. Given that chronic hepatitis C affects globally around 20% of HIV persons, major attention has been focused on the HIV/HCV-coinfected population. Current evidence suggests that these patients depict cure rates of over 90%, similar to HCV-monoinfected individuals (Sulkowski, et al. JAMA. 2014; 312:353-61). Accordingly, current guidelines for hepatitis C therapy no longer separate mono- and coinfected subjects.

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