Cellular and Immune Therapy for Treating HIV-1 Infection
Wei Li 1, Qiqiang Zhou 1, Lingbo Xia 1, Ruixiang Zou 1, Wei Zou 2
1 The First Clinical Medical College of Nanchang University, Nanchang, China; 2 Department of Infectious Diseases, The 1st Affiliated Hospital of Nanchang University, Nanchang, China
*Correspondence: Lingbo Xia, Email not available
Abstract
At present, HIV-1 infection is treated with combined antiretroviral therapy (cART). cART greatly improves the life quality and outcome of infected individuals but cannot eradicate the virus from the hosts. Therefore, new treatment methods that can clear the virus are needed. In this review, we summarized four novel approaches that have the potentials to cure HIV infection, which are dendritic cell targeting, CCR5 editing, LASER ART, and CRISPR-cas9 dual therapy and broad neutralization antibodies.
